| Photo of the class | Regional Science Fair | State Science Fair |
| BioGENEius Challenge |
Seminar presentations | ISEF |
Lanre Adekola (class of 2009) worked in Department of Civil Engineering at the University of Minnesota St. Anthony Falls Laboratory under the supervision of Dr. John Gulliver. Lanre studied the effects of soil compaction on absorption rates of rainwater into soil, investigating ways in which low absorption rates lead to polluted runoff. Urban runoff is a significant pollution source due to the impervious nature of urban developments. Lanre participated in urban runoff study at the Minnetonka Regional Park to assess urban runoff management practices. He also undertook a synthetic runoff test where he designed and then constructed a device to measure water infiltration into in compacted soil versus soil that had been tilled and composed. Lanre concluded that an effective method for improving water absorption rates and reducing runoff is tilling and composting of soil. Lanre's paper, PowerPoint, and poster can be accessed here. |
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| Michael Crump (class of 2009) worked in the Chemical Engineering and Materials Science Department at the University of Minnesota under the supervision of Dr. Russell Holmes. Michael’s goal was to improve the efficiency of thin-layer organic photovoltaic (PV) cells by increasing voltage without decreasing current. He fabricated PV cells in a vacuum chamber by subliming various thicknesses of an organic layer of naphthyl-phenyl-diamine (NPD) onto copper phthalocyanine and fullurene-C60. After experimenting with NPD, Michael sublimed various thicknesses of platinum octaethylporphyrin (PtOEP). His results showed a loss in current with a small increase in voltage for both cells, indicating that neither NPD nor PtOEP are effective thin-layer organics for improving efficiency of PV cells with the cell structure that he used. However, his results suggest that a higher efficiency can be achieved by restructuring the organic layers so that they are blended together rather than applied separately. His work is a first step in fabricating higher-efficiency solar cells to reduce use of fossil fuels as a source of electricity and consequently to slow global warming. Michael's paper, PowerPoint, and poster can be accessed here. | |
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Sierra Danforth (class of 2009) and Sahar Hakim-Hashemi (class of 2009) collaborated on a project under the guidance of Dr. George Heimpel in the Department of Entomology at the University of Minnesota. The goal of their project was to determine if a parasitic wasp, Lyiphlebus sp. nr. testaceipes, could be safely used to biologically control invasive soybean aphids that have infested 70% of Midwestern soybean crops. Working in a quarantine area, Sierra and Sahar infested soybean plants with soybean aphids and then introduced Lysiphlebus wasps to test the effectiveness of the wasps in eradicating the invasive aphids. They also introduced the Lysiphlebus wasps to non-targeted aphids to determine attack rates. Their results showed that the Lysiphlebus wasp is an effective biological-control agent for invasive soybean aphids while not harming non-targeted aphids, indicating that the Lyiphlebus wasp can be safely released to protect soybean crops. Sierra's paper, PowerPoint, and poster can be accessed here. |
| Michael Fuad (class of 2009) worked at the Center for Bio-refining at the University of Minnesota under the direction of Dr. Roger Ruan. Michael engineered an improved method to harvest algae for production of biodiesel. His method was based on wastewater treatment techniques, where chemicals are used to destabilize microparticles in suspensions, causing them to flocculate. Michael added combinations of hydrochloric acid, aluminum sulfate, and high-cationicity polyacrylamides to successfully coagulate and flocculate algae from suspension. His method will be applied to industrial processes to more effectively and economically produce biodiesel from algae. Michael's paper, PowerPoint, and poster can be accessed here. | |
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Sahar Hakim-Hashemi (class of 2009) and Sierra Danforth(class of 2009) collaborated on a project under the guidance of Dr. George Heimpel in the Department of Entomology at the University of Minnesota. The goal of their project was to determine if a parasitic wasp, Lyiphlebus sp. nr. testaceipes, could be safely used to biologically control invasive soybean aphids that have infested 70% of Midwestern soybean crops. Working in a quarantine area, Sierra and Sahar infested soybean plants with soybean aphids and then introduced Lysiphlebus wasps to test the effectiveness of the wasps in eradicating the invasive aphids. They also introduced the Lysiphlebus wasps to non-targeted aphids to determine attack rates. Their results showed that the Lysiphlebus wasp is an effective biological-control agent for invasive soybean aphids while not harming non-targeted aphids, indicating that the Lyiphlebus wasp can be safely released to protect soybean crops. Sahar's paper, PowerPoint, and poster can be accessed here. |
| Xin Li (class of 2009) continued research into a second year, working in the Department Plant Biology at the University of Minnesota under the supervision of Dr. Sue Gibson. Xin characterized sugar-response in Arabidopsis seedlings with the goal of engineering soybean plants to produce higher yields ethanol, soy protein, and soydiesel. She planted Arabidopsis mutant seeds, which had defective genes at known locations in plant genomes, in 6% sugar media and then measured root growth and anthocyanin levels of the mutant seedlings compared to control Arabidopsis seedlings. She identified one mutant gene, gte4, that was hypersensitive to sucrose. She used anthocyanin and sis assays to verify that the high anthocyanin levels and short root growth were caused by the mutant gene. She was then able to characterize the mutant gene using PCR and abscisic acid assays. Xin's paper, PowerPoint, and poster can be accessed here. | |
| Daniel Mokhtari (class of 2010) continued research into a second year, conducting research in the Department of Chemistry at Hamline University under the supervision of Dr. John Matachek. Daniel designed and then began the synthesis of a ferrocene-thiophene organomettalic compound that can be used as a “sniffing” molecule to identify hazardous organic compounds and heavy metals. His research involved developing practical applications for this molecule as a water-quality test for heavy metal cations, a quick test for various pathogens, or a new method to deliver radioactive metal cations to specific locations for cancer treatment. Daniel experimented with coupling methods to synthesize the compound, including Grignard reactions, Stille coupling, and coupling using glucal-epoxides. He was successful in constructing the ferrocene-thiophene portion of the molecule using epoxide coupling, which is the first step in synthesizing the organometallic sniffing compound. Daniel's paper, PowerPoint, and poster can be accessed here. | |
| Emily Nimmer (class of 2009)
continued research into a second year, working at the University of Minnesota Department of Fisheries, Wildlife, and Conservation Biology under the supervision of Dr. Karen Oberhauser. She investigated potential effects of climate change on monarch butterflies, specifically looking how higher nighttime temperatures (30 °C) paired with high daytime temperatures (38 °C) affect monarch development. She found that high nighttime temperatures did not have a significant effect on larval survival, larval development, or adult butterfly health. By understanding how rising temperatures will affect the monarch butterfly population, Emily’s study contributed important information on the impact of climate change and its effect on insect populations around the world. Emily's paper, PowerPoint, and poster can be accessed here. |
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| Travis Spangler (class of 2009) worked at the Masonic Cancer Research Center at the University of Minnesota under the supervision of Dr. Daniel Vallera. The purpose of Travis’ study was to determine if a new cancer drug called DTEGFATF, a bispecific cytotoxin, is more effective in killing glioblastoma brain-tumor cells than current chemotherapy drugs that use monospecific counterparts of the bispecific cytotoxin. Travis ran multiple assays using each cytotoxin on brain tumor cell lines. He determined that the bispecific cytotoxin is significantly more effective in killing brain tumor cells than using the two cytotoxins separately. Travis' paper, PowerPoint, and poster can be accessed here. | |
Madelaine Taft-Ferguson (class of 2009) continued research into a second year, working at the Diabetes Institute of Immunology and Transplantation in the laboratory of Dr. Pratima Bansal-Pakala at the University of Minnesota. The goal of Madelaine’s research was to determine if transplants using islet donor cells from pigs are as effective in treating diabetes as current treatments that involve transplanting islet cells form human donors. Madelaine ran intracellular cytokine staining assays that she analyzed using flow cytometry to measure cytokine levels, which are indicators of immune reaction. She found that human cells produced more of the cytokines IFN-gamma, perforin, and granzyme B when stimulated with human donor cells but produced more IL-17 and TRAIL when stimulated with pig donor cells. Madelaine’s research is a first step in making islet transplants far more accessible to diabetes patients through use of donor cells from pigs rather than from human donors. Madelaine's paper, PowerPoint, and poster can be accessed here. |
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| Stephen Trusheim (class of 2009) continued research into a second year, working at Access Genetics under the supervision of Dr. Ron McGlennen. The goal of his project was to design a novel method for hospitals to use when testing for Methicillin-resistant Staphylococcus aureus (MRSA). He engineered computer software that predicts MRSA-colonized patients upon hospital admission, allowing hospitals to identify > 90% of MRSA cases by testing 50% of admitted patients — a strategy he termed “predictive MRSA surveillance.” Stephen validated the impact of his new strategy by engineering accurate hospital cost analyses; results show that predictive MRSA surveillance can save 25% of hospital MRSA-testing costs without decreasing quality of patient care. Stephen’s software allows more hospitals to afford MRSA surveillance, a technique proven to reduce the incidence of this deadly endemic disease. Stephen's paper, PowerPoint, and poster can be accessed here. |